The Method To Solve The Sticking And Punching Problem of Tablet Press

As we all know, sticking and punching are common problems in the production process of tablet presses, which not only affect production efficiency but may also lead to a decrease in product quality. The following is a detailed introduction to the methods and preventive measures to solve the problem of sticking andpunching in tablet presses:

The method to solve the sticking and punching problem of tablet press：

1. Control material humidity: Excessive material humidity is one of the main causes of sticking and flushing. The humidity of materials should be strictly 

controlled to ensure that it is within an appropriate range, generally around 2% -3%.

2. Optimize the surface of the stamping die: Insufficient roughness or residual rust proof oil, lubricating oil, etc. on the surface of the stamping die may cause

 material adhesion. Regularly inspect and maintain the punching die, keep its surface smooth and clean, and polish it if necessary. For new stamping dies, due to the smaller gap, it may be easier to trap air and cause sticking.

3. Adjust the operating parameters of the tablet press: Improper setting of the operating parameters of the tablet press, such as excessive pressure or fast speed, may cause sticking and punching. The operating parameters of the tablet press should be adjusted reasonably according to the characteristics of the materials and production requirements, to avoid excessive or insufficient pressure and speed.

4. Use appropriate lubricants: Improper selection or insufficient use of lubricants cannot effectively reduce friction between materials, leading to adhesive flushing. The material formula should be optimized by adding an appropriate amount of lubricant (such as magnesium stearate, PEG6000, etc.) to reduce friction between materials.

5. Improve environmental conditions: Excessive humidity in the operating room or workshop can increase the adhesion of materials and equipment, leading to adhesive flushing. The humidity and temperature in the operating room or workshop should be controlled to maintain suitable environmental conditions.

6. Handling special situations: such as preheating the punch with an empty machine, applying magnesium stearate before production, and other special operations. If theparticles are stored for too long and become damp, they should be promptly compressed or appropriate moisture-proof measures should be taken.

Measures to prevent sticking and punching problems in tablet presses

1. Regular cleaning and maintenance of tablet press: Regularly clean and maintain the tablet press to ensure its normal operation. This includes removing residual materials and lubricants from the die, as well as inspecting and replacing worn parts.

2. Strengthen the training and management of operators: Strengthen the training and management of operators, improve their operational skills and safety awareness. Operators should be familiar with the operation process and maintenance requirements of the equipment, as well as the characteristics of the product, and be able to promptly detect and handle adhesive problems.

3. Optimize material formula and mixing process: Optimize the granulation process to achieve the quality requirements of the variety in terms of fineness, and control the mixing time. This helps to reduce the amount of fine powder, improve the flowability of the material, and enhance the compressibility of the tablet.

4. Monitor key parameters in the production process: Real time monitoring of key parameters in the production process, such as pressure, temperature, humidity, etc., to ensure that they are within the control range. This helps to promptly identify changes in conditions that may cause sticking and take corresponding adjustment measures.

5. Adopting advanced tablet pressing technology: Adopting advanced tablet pressing technology such as pre pressing technology, coating technology, conical die design, etc., can help reduce the occurrence of sticking and punching. These technologies can improve air discharge and reduce particle retention in the die. 6. Preventive measures during the R&D phase: Design a prescription to avoid sticking and flushing during the R&D phase, and have a deep understanding of material properties and process characteristics. This includes selecting appropriate excipients, optimizing granulation processes, adjusting particle size distribution, etc.